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Mydriasis - dilation of the pupil, induced by drugs - LSD, amphetamine, cocaine, MDMA, mephedrone

Mydriasis - dilation of the pupil, induced by drugs - LSD, amphetamine, cocaine, MDMA, mephedrone MMR vaccine Micropenis Asperger's -- Mydriasis is the dilation of the pupil. Non-physiological causes of mydriasis include disease, trauma, or the use of drugs. Drugs that can cause mydriasis include: Serotonergics such as LSD, psilocybin mushrooms, mescaline and 2C-B. These drugs are typically hallucinogens. Similarly, selective serotonin reuptake inhibitors can cause mydriasis.

Drugs

A mydriatic is an agent that induces dilation of the pupil. Drugs such as tropicamide are used in medicine to permit examination of the retina and other deep structures of the eye, and also to reduce painful ciliary muscle spasm (see cycloplegia). One effect of administration of a mydriatic is intolerance to bright light (photophobia). Purposefully-induced mydriasis via mydriatics is also used as a diagnostic test for Horner's syndrome.

Mydriasis can be induced via modulation of adrenergic or cholinergic signalling.

Drugs that can cause mydriasis include:

Stimulants (typically monoaminergics) such as amphetamines, cocaine, MDMA, and mephedrone.
Anticholinergics such as diphenhydramine, atropine, hyoscyamine, and scopolamine antagonize the muscarinic acetylcholine receptors in the eye. Blocking acetylcholine receptors, reduces the pupilary muscles' ability to constrict and causes dilation (which is critical in eye surgery procedures such as cataract surgery which require uninterrupted access to the inner eye via the pupilary aperture, thus requiring that the eye be both paralyzed and anesthetized before the procedure can go ahead. The antimuscarinic, tropicamide, may be used as a mydriastic agent during surgery.[5]
Serotonergics such as LSD, psilocybin mushrooms, mescaline and 2C-B. These drugs are typically hallucinogens. Similarly, selective serotonin reuptake inhibitors can cause mydriasis.
Dissociatives such as dextromethorphan (an SSRI and sigma-1 agonist).
Certain GABAergic drugs, such as phenibut and GHB.
Adrenergic agonists, such as phenylephrine and cyclomydril.[6] Adrenergic agonists may be used if strong mydriasis is needed in surgery.[7] Norepinephrine is a hormone and neurotransmitter that regulates the involuntary muscles of the autonomic nervous system, including dilation of the pupil aperture via the muscles of the iris. Hence adrenergic agonists mimic the activity of norepinephrine, which is how they induce mydriasis.

Natural release of the hormone oxytocin can cause mild to moderate mydriasis.[citation needed]

Long term effects of drugs can also cause mydriasis, for example opioid withdrawal.


MILJØFORKJEMPER: Greta Thunberg er i California og ikke selv til stede på prisgallaen. Foto Michael Campanella / Getty Images Europe
Greta Thunberg nekter å ta imot prisen fra Nordisk råd – refser blant annet Norge -- Norske Kristin Roskifte (44) ble tirsdag kveld belønnet med Nordisk råds pris for barne- og ungdomslitteratur. Svenske Greta Thunberg (16) vant miljøprisen, men nekter å ta imot den.
Catherine Gonsholt Ighanian
Oppdatert 29. oktober
Greta Thunberg: – Trenger ikke flere priser

Svenske Greta Thunberg (16) ble ropt opp som vinner av Nordisk råds miljøpris. Den unge miljøaktivisten hedres for å ha mobilisert millioner av mennesker over hele verden til å kreve handling.


Refser Norge

Etter at nyheten ble kjent, postet Thunberg følgende melding med hele talen på Instagram. Der langer hun blant annet ut mot Johan Sverdrup-feltet, som skal pumpe opp olje for 1400 milliarder kroner i 50 år (artikkelen fortsetter under bildet)

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